Centre for Misfolding Diseases

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  • Currently displaying 121 - 140 of 2350 publications
Author(s)
Publication title
Journal Name
Publication year
Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers.
J Nielsen, J Lauritsen, JN Pedersen, JS Nowak, MK Bendtsen, G Kleijwegt, K Lusser, LC Pitarch, JV Moreno, MM Schneider, G Krainer, L Goksøyr, P Khalifé, SS Kaalund, S Aznar, M Kjærgaard, V Sereikaité, K Strømgaard, TPJ Knowles, MA Nielsen, AF Sander, M Romero-Ramos, DE Otzen
Npj Parkinson S Disease
(2024)
10
(doi: 10.1038/s41531-024-00747-6)
Estimation of ligand binding free energy using multi-eGO.
B Stegani, E Scalone, F Bacic Toplek, T Lohr, S Gianni, M Vendruscolo, R Capelli, C Camilloni
(2024)
(doi: 10.26434/chemrxiv-2024-jcmgc)
On-demand thio-succinimide hydrolysis for the assembly of stable protein–protein conjugates
AV Vasco, RJ Taylor, Y Méndez, GJL Bernardes
J Am Chem Soc
(2024)
146
(doi: 10.1021/jacs.4c03721)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
Nature Communications
(2024)
15
(doi: 10.1038/s41467-024-48496-7)
Thermodynamic profiles for cotranslational trigger factor substrate recognition.
TW Herling, AME Cassaignau, AS Wentink, QAE Peter, PC Kumar, T Kartanas, MM Schneider, LD Cabrita, J Christodoulou, TPJ Knowles
Science Advances
(2024)
10
(doi: 10.1126/sciadv.adn4824)
Protein Condensate Atlas from predictive models of heteromolecular condensate composition.
KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles
Nature Communications
(2024)
15
(doi: 10.1038/s41467-024-48496-7)
Preparation and Characterization of Zn(II)-Stabilized Aβ<sub>42</sub> Oligomers.
A González Díaz, R Cataldi, B Mannini, M Vendruscolo
ACS chemical neuroscience
(2024)
15
(doi: 10.1021/acschemneuro.4c00084)
Biomolecular condensates are characterized by interphase electric potentials.
AE Posey, A Bremer, NA Erkamp, A Pant, TPJ Knowles, Y Dai, T Mittag, RV Pappu
(2024)
(doi: 10.1101/2024.07.02.601783)
Step Forward Cross Validation for Bioactivity Prediction: Out of Distribution Validation in Drug Discovery
US Saha, M Vendruscolo, AE Carpenter, S Singh, A Bender, S Seal
(2024)
(doi: 10.1101/2024.07.02.601740)
α-synuclein oligomers displace monomeric α-synuclein from lipid membranes
G Šneiderienė, MA Czekalska, CK Xu, AK Jayaram, G Krainer, WE Arter, QAE Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles
ACS nano
(2024)
18
(doi: 10.1021/acsnano.3c10889)
The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A
C Olivieri, Y Wang, C Walker, MV Subrahmanian, KN Ha, D Bernlohr, J Gao, C Camilloni, M Vendruscolo, SS Taylor, G Veglia
eLife
(2024)
12
(doi: 10.7554/elife.91506.3)
The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A.
C Olivieri, Y Wang, C Walker, MV Subrahmanian, KN Ha, D Bernlohr, J Gao, C Camilloni, M Vendruscolo, SS Taylor, G Veglia
eLife
(2024)
12
(doi: 10.7554/eLife.91506)
Hierarchical Protofilament Intertwining Rules the Formation of Mixed-Curvature Amyloid Polymorphs
J Zhou, S Assenza, M Tatli, J Tian, IM Ilie, EL Starostin, A Caflisch, TPJ Knowles, G Dietler, FS Ruggeri, H Stahlberg, SK Sekatskii, R Mezzenga
Adv Sci (Weinh)
(2024)
11
(doi: 10.1002/advs.202402740)
The Cystic Fibrosis Transmembrane Regulator Controls Tolerogenic Responses to Food Allergens in Mice and Humans
M Emmenegger, C Zografou, Y Dai, L Hoyt, R Gudneppanavar, A Chincisan, H Rehrauer, F Noé, N Zajac, G Meisl, M Schneider, H Nguyen, K Höpker, T Knowles, M Sospedra, R Martin, A Ring, S Leeds, S Eisenbarth, M Egan, E Bruscia, A Aguzzi
(2024)
(doi: 10.1101/2024.06.17.24309019)
Electrolyte-gated organic field-effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández-Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
Smartmat
(2024)
5
(doi: 10.1002/smm2.1291)
The role of shear forces in primary and secondary nucleation of amyloid fibrils
E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, G Šneiderienė, D Thacker, TPJ Knowles, E Sparr, S Linse
Proc Natl Acad Sci U S A
(2024)
121
(doi: 10.1073/pnas.2322572121)
Electrolyte‐gated organic field‐effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández‐Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
SmartMat
(2024)
5
(doi: 10.1002/smm2.1291)
Biomolecular condensates with complex architectures via controlled nucleation
NA Erkamp, MAM Verwiel, D Qian, T Sneideris, FA Spaepen, DA Weitz, JCM van Hest, TPJ Knowles
Nature Chemical Engineering
(2024)
1
(doi: 10.1038/s44286-024-00077-7)
Identification of high-affinity secondary nucleation inhibitors of Aβ42 aggregation from an ultra-large chemical library using Deep Docking
M Vendruscolo, M Brezinova, F Brotzakis, R Horne, VR Chowdhury, R Gregory, F Gentile
(2024)
(doi: 10.21203/rs.3.rs-4512167/v1)
The diversity ofSNCAtranscripts in neurons, and its impact on antisense oligonucleotide therapeutics
JR Evans, EK Gustavsson, I Doykov, D Murphy, GS Virdi, J Lachica, A Röntgen, MH Murtada, CW Pang, H Macpherson, AI Wernick, CE Toomey, D Athauda, ML Choi, J Hardy, NW Wood, M Vendruscolo, K Mills, W Heywood, M Ryten, S Gandhi
(2024)
(doi: 10.1101/2024.05.30.596437)
Yusuf Hamied Department of Chemistry
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