Centre for Misfolding Diseases

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  • Currently displaying 361 - 380 of 2350 publications
Author(s)
Publication title
Journal Name
Publication year
Hsc70 mediated disaggregation of α-synuclein fibrils
MM Schneider, S Gautam, TW Herling, G Krainer, E Andrzejewska, A Bracher, CM Dobson, U Hartl, TP Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.2605)
Sequence-based prediction and measurement of pH-dependent protein solubility
M Oeller, P Sormanni, M Vendruscolo
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.989)
Rate‐limiting processes of tau aggregate accumulation in Alzheimer's disease
G Meisl, Y Zuo, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, T Knowles, D Klenerman
Alzheimer's & Dementia
(2022)
17
(doi: 10.1002/alz.051680)
Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics
R Khetan, R Curtis, CM Deane, JT Hadsund, U Kar, K Krawczyk, D Kuroda, SA Robinson, P Sormanni, K Tsumoto, J Warwicker, ACR Martin
MAbs
(2022)
14
(doi: 10.1080/19420862.2021.2020082)
Using microscopy techniques to structurally characterise TDP-43 inclusions present in mammalian cell models
NS Matharu, CW Chung, JR Kumita, GS Kaminski, TP Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.1401)
Mechanism of secondary nucleation from the direct observation of Aβ42 aggregation at the single fibril level
MR Zimmermann, SC Bera, G Meisl, S Dasadhikari, S Ghosh, S Linse, K Garai, TPJ Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.556)
Therapeutic drug targeting in Alzheimer's disease
R Geiser, M Sanguanini, R Staats, D Rinauro, M Metrick, P Ciryam, S Casford, E Zhao, J Fleming, S Hunter, C Brayne, M Vendruscolo
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.1785)
Simultaneous fractionation and characterization of pre-fibrillar aggregates in solution with single-molecule microfluidics
EA Andrzejewska, G Krainer, CK Xu, R Jacquat, MM Schneider, W Arter, TPJ Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.1003)
Transition metal mediated bioorthogonal release
V Sabatino, VB Unnikrishnan, GJL Bernardes
Chem Catalysis
(2022)
2
(doi: 10.1016/j.checat.2021.12.007)
A Machine Learning Approach to Identify Small Molecule Inhibitors of Secondary Nucleation in α-Synuclein Aggregation
R Horne, A Possenti, S Chia, F Brotzakis, R Staats, M Nowinska, M Vendruscolo
(2022)
(doi: 10.21203/rs.3.rs-1236129/v1)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g-v2)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
Nano letters
(2022)
22
(doi: 10.1021/acs.nanolett.1c03138)
Controlled In‐Cell Generation of Active Palladium(0) Species for Bioorthogonal Decaging
J Konč, V Sabatino, E Jiménez‐Moreno, E Latocheski, LR Pérez, J Day, JB Domingos, GJL Bernardes
Angewandte Chemie
(2022)
134
(doi: 10.1002/ange.202113519)
Modulators of the plasma membrane protect cells from diverse toxic agents, ranging from protein misfolded oligomers to pore forming agents
R Limbocker, RP Kreiser, LR Sasser, AK Wright, DJ Rinauro, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Kinetic analysis of tau aggregation for drug discovery
DJ Rinauro, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Counteraction of amyloid-β aggregation by vitamin A and E metabolites in a crowded environment
P Joshi, S Chia, X Yang, M Perni, J Habchi, M Vendruscolo
BIOPHYSICAL JOURNAL
(2022)
121
Sequence-Based Prediction of Ph-Dependent Protein Solubility Using Camsol
M Oeller, R Kang, R Bell, H Ausserwoger, P Sormanni, M Vendruscolo
SSRN Electronic Journal
(2022)
(doi: 10.2139/ssrn.4189397)
Microchip Free-Flow Electrophoresis for Bioanalysis, Sensing, and Purification.
WE Arter, KL Saar, TW Herling, TPJ Knowles
(2022)
2394
(doi: 10.1007/978-1-0716-1811-0_16)
Comparative study of the affinities of natural aminosterols for lipid membranes and their relation with protection from misfolded protein oligomers
S Errico, L Neri, G Lucchesi, D Odino, G Caminati, A Relini, M Zasloff, M Vendruscolo, F Chiti
FEBS OPEN BIO
(2022)
12
Yusuf Hamied Department of Chemistry
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CB2 1EW
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