Centre for Misfolding Diseases

Publications

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  • Currently displaying 221 - 240 of 2350 publications
Author(s)
Publication title
Journal Name
Publication year
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, M Schneider, T Welsh, J Fan, Q Peter, E Andrzejewska, G Šneiderienė, M Czekalska, H Ausserwoeger, L Chai, W Arter, K Saar, T Herling, T Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, S Lee, TPJ Knowles
(2023)
(doi: 10.1101/2023.07.12.548675)
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes
S Errico, G Lucchesi, D Odino, EY Osman, R Cascella, L Neri, C Capitini, M Calamai, F Bemporad, C Cecchi, WA Kinney, D Barbut, A Relini, C Canale, G Caminati, R Limbocker, M Vendruscolo, M Zasloff, F Chiti
J Med Chem
(2023)
66
(doi: 10.1021/acs.jmedchem.3c00182)
Self-replication of Aβ42aggregates occurs on small and isolated fibril sites
S Curk, J Krausser, G Meisl, D Frenkel, S Linse, T Michaels, T Knowles, A Šarić
(2023)
(doi: 10.1101/2023.07.05.547777)
Amyloid formation as a protein phase transition
TCT Michaels, D Qian, A Šarić, M Vendruscolo, S Linse, TPJ Knowles
Nature Reviews Physics
(2023)
5
(doi: 10.1038/s42254-023-00598-9)
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics
DB Morse, AM Michalowski, M Ceribelli, J De Jonghe, M Vias, D Riley, T Davies-Hill, T Voss, S Pittaluga, C Muus, J Liu, S Boyle, DA Weitz, JD Brenton, JD Buenrostro, TPJ Knowles, CJ Thomas
Cell systems
(2023)
14
(doi: 10.1016/j.cels.2023.05.003)
Amyloids and protein aggregation.
S Linse, T Knowles
Chem Sci
(2023)
14
(doi: 10.1039/d2sc90225g)
Extracellular protein homeostasis: The dawning of a new age for human disease therapies?
MR Wilson, S Satapathy, M Vendruscolo
Clin Transl Med
(2023)
13
(doi: 10.1002/ctm2.1305)
Formation of Protein Nanoparticles in Microdroplet Flow Reactors.
Q Zhang, Z Toprakcioglu, AK Jayaram, G Guo, X Wang, TPJ Knowles
ACS Nano
(2023)
17
(doi: 10.1021/acsnano.3c00107)
Understanding and controlling the molecular mechanisms of protein aggregation in mAb therapeutics
KT Pang, YS Yang, W Zhang, YS Ho, P Sormanni, TCT Michaels, I Walsh, S Chia
Biotechnology advances
(2023)
67
(doi: 10.1016/j.biotechadv.2023.108192)
Thermodynamic and kinetic approaches for drug discovery to target protein misfolding and aggregation
M Vendruscolo
Expert Opin Drug Discov
(2023)
18
(doi: 10.1080/17460441.2023.2221024)
De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, L Tatalick, P Ruivo, MP de Miranda, A Gomes, T Carvalho, MJ Walker, H Ausserwoeger, J Pedro Simas, M Veldhoen, TPJ Knowles, D-A Silva, D Shoultz, GJL Bernardes
Journal of Infectious Diseases
(2023)
228
(doi: 10.1093/infdis/jiad135)
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, T Welsh, T Sneideris, T Franzmann, S Qamar, N Erkamp, J Nixon-Abell, M Kar, PS George-Hyslop, A Hyman, S Alberti, R Pappu, T Knowles
(2023)
(doi: 10.1101/2023.05.31.543137)
Unlocking the Potential of Bio-Based Nitrogen-Rich Furanic Platforms as Biomass Synthons
RFA Gomes, BMF Gonçalves, KHS Andrade, BB Sousa, N Maulide, GJL Bernardes, CAM Afonso
Angew Chem Int Ed Engl
(2023)
62
(doi: 10.1002/anie.202304449)
Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration
S Koga, MA Metrick, LI Golbe, A Santambrogio, M Kim, AI Soto-Beasley, RL Walton, MC Baker, CF De Castro, M DeTure, D Russell, BA Navia, C Sandiego, OA Ross, M Vendruscolo, B Caughey, DW Dickson
Acta Neuropathol Commun
(2023)
11
(doi: 10.1186/s40478-023-01584-z)
Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons
RFA Gomes, BMF Gonçalves, KHS Andrade, BB Sousa, N Maulide, GJL Bernardes, CAM Afonso
Angewandte Chemie
(2023)
135
(doi: 10.1002/ange.202304449)
CAID prediction portal: a comprehensive service for predicting intrinsic disorder and binding regions in proteins.
A Del Conte, A Bouhraoua, M Mehdiabadi, D Clementel, AM Monzon, CAID predictors, SCE Tosatto, D Piovesan
Nucleic Acids Research
(2023)
51
(doi: 10.1093/nar/gkad430)
α-Synuclein oligomers form by secondary nucleation
C Xu, G Meisl, E Andrzejewska, G Krainer, A Dear, MC Cruz, S Turi, R Jacquat, W Arter, M Vendruscolo, S Linse, TPJ Knowles
(2023)
(doi: 10.1101/2023.05.28.542651)
Towards sequence-based principles for protein phase separation predictions
M Vendruscolo, M Fuxreiter
Curr Opin Chem Biol
(2023)
75
(doi: 10.1016/j.cbpa.2023.102317)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains
A Miller, J Wei, S Meehan, CM Dobson, ME Welland, D Klenerman, M Vendruscolo, FS Ruggeri, TPJ Knowles
Proceedings of the National Academy of Sciences
(2023)
120
(doi: 10.1073/pnas.2216234120)
Theoretical and Data-Driven Approaches for Biomolecular Condensates.
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
Chemical reviews
(2023)
123
(doi: 10.1021/acs.chemrev.2c00586)
Yusuf Hamied Department of Chemistry
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